Sanger Projects

Genome assemblies for 25 species across the Notothenioid radiation.

The notothenioids (suborder: Notothenioidei), are a group of Percomorph fish and one of the best characterized marine adaptive radiations. Notothenioids consist ...

Open-access data portals

The Cellular Genetics Programme is committed to making cell atlasing data analysis and visualisation tools available to the scientific community

Open access tools

Computational tools developed by the research groups and scientific teams of the Cellular Genetics Programme

originally developed in Martin Hemberg's group

Cellular Genetics scRNA-seq analysis course

Combinatorial screen in a panel of mesothelioma cell lines

We have carried out a combinatorial screen in a panel of mesothelioma cell lines of 2,697 2-drug combinations and ...

Our plasmid collections can be browsed and ordered from our EXtracellular Plasmid RESource (EXPRESs) at Addgene.

The hematopoietic system provides a good model system to inform interpretation of association studies owing to simple phenotypes at the ...

As the impact of the human reference genome assembly on biomedical research has shown, the availability of a high quality ...

The use of genome-wide forward genetic screens to define the landscape of drug resistance drivers in cancer.

Cancer Ageing and Somatic Mutation research

In collaboration with the Andrea Bertotti lab at University of Turin we plan to sequence 500 human colorectal PDX models.

Whole genome and targeted gene screens in primary and recurrent anaplastic meningiomas.

We are using siKinome and genome-wide CRISPR/Cas9 lethality screens in colorectal cancer cell lines to identify novel vulnerabilities.

The genomics of rapid speciation in Lake Malawi cichlids

Genome sequences of cichlid fish for studies in speciation and evolutionary genomics

HAVANA team

The HAVANA team manually annotate the human, mouse, zebrafish and other vertebrate genomes.

Mapping single cell transcriptomes in the intra-tumoural and associated territories of kidney cancer

This project charts the heterogeneity in the microenvironment in kidney cancer using single cell RNA sequencing, spatial transcriptomics, and whole exome ...

This is a collection of OME-Zarr backed visualizations for bioimaging data

This is a collection of datasets from the Sanger Institute that have been converted to OME-Zarr to test and encourage the ...

PlasmoGEM provides the malaria research community with a variety of resources currently focusing on P.berghei , P falciparum and P. ...

Miska Lab

This line of research pursues the identification of major molecular players involved in epigenetic inheritance in mammals. We are especially interested ...

Initiative to gather all known information about sexual reproduction acrros the tree of eukaryotic life

Tree of Sex is a large initiative to gather reproductive data for all Eukaryotic species across the tree of life.

Datasets and code from Trynka group

Links to codes, data visualisation and datasets

The Vertebrate Genomes Project

The Vertebrate Genomes Project (VGP) at the Sanger Institute aims to provide reference quality assemblies for hundreds of fish, rodents ...

 COVID-19 Surveillance Team

The SARS-CoV2 genome sequences produced by the Wellcome Sanger Institute were the result of a team effort by many people from ...

Wellcome Trust Strategic Award - The Homunculus in our Thymus: A Cellular Genomics Approach

We have been granted a strategic award from the Wellcome Trust 'The Homunculus in our Thymus: A Cellular Genomics Approach' that ...

Miska Lab

This project aims at elucidating the function of piRNAs - small germline-specific non-coding RNAs - in different vertebrates.