Marioni Group

Single cell genomics

John Marioni's group develop computational and statistical tools to exploit high-throughput genomics data to understand the regulation of gene expression and to model developmental and evolutionary processes. His team has pioneered approaches for analysing single-cell transcriptomics data and, together with four colleagues, he co-ordinates the Sanger Institute-EBI Single-Cell Genomics Centre.

Our people

Previous group lead

Dr John Marioni

Former Associate Faculty

Associated research

Collaborations

Collaboration

Sanger Institute-EBI Single-Cell Genomics Centre

We are developing and applying methods to explore the genome, epigenome and transcriptome of single cells in order to better understand ...

Projects

Research project

Wellcome Trust Strategic Award - The Homunculus in our Thymus: A Cellular Genomics Approach

We have been granted a strategic award from the Wellcome Trust 'The Homunculus in our Thymus: A Cellular Genomics Approach' that ...

Related groups

Science group

Reik Group

Epigenetic reprogramming

Single cell epigenomics applied to development and ageing

Science group

Voet Group

Single-cell genomics

Thierry Voet's group focuses on developing methods that characterise the DNA and RNA in a single cell to enable ...

Science group

Bird Group

Epigenetic mechanisms in health and disease

Adrian's group is investigating "The function of long non-coding RNAs originating at CpG island promoters" and "The effects of ...

Science group

Single Cell Genomics Core Facility

Scientific Operations

Our aim is to offer a high-quality, high-throughput single cell sequencing service that enables Faculty to study and understand cellular heterogeneity ...

Wellcome Sanger Institute

Programmes and Facilities

Programme

Cellular Genetics

We combine cutting-edge single-cell genomics at scale with advanced computational methods, including machine learning and artificial intelligence, to understand the human ...

Publications

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