Global Human Diversity

We are engaged in a programme of studies assessing cultural and genetic diversity and disease patterns among worldwide indigenous populations to provide further insight into human history and increase our understanding of the environmental, physical and biological adaptations that characterise disease susceptibility.

Understanding the genetic determinants of complex human traits and diseases can lead to novel insights into disease aetiology, which may identify new therapeutic targets, and the potential for better disease prognosis and management.

This work builds on our existing research programmes, and those of our collaborating partners, which include the identification of novel genetic signals for cardiometabolic traits in populations from sub-Saharan Africa including those that are specific to the African continent; the development of the largest study of indigenous populations across sub-Saharan Africa; and population scale sequencing of human populations across South East Asia and Oceania.

Individual Projects

For more information about specific projects within our programme of research activities please refer to the individual profile pages of our group members.

Further information

Enquiries about the group, its research and training opportunities should be sent by email to Paris Litterick (pl7@sanger.ac.uk).